The activation of generic substitution was a daily issue at the National Assembly Health and Welfare Committee's national audit held on the 7th to 8th and 13th. It has been a long time since 2015 that the National Assembly has been interested in revitalizing alternative preparations as much as this year. This is also the reason why Young-Seok Seo, a member of Democratic Party of Korea initiated the 'Pharmaceutical Affairs Law Amendment Bill', which allows post-notification to the prescriber or the HIRA after generic substitution.

According to the announcement of The MFDS, Pharmacists can make a generic substitution with an item recognized as bioequivalence by the MFDS or a bioequivalence reference drug