The Effects and Challenges of Vitrakvi
By | translator Choi HeeYoung
21.07.16 06:00:20
가나다라
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The first NTRK targeted treatment, same effectiveness as adults in children
Need to verify cancer efficacy
In May, the Cancer Drugs Benefit Appraisal Committee passed, paying attention to whether the drug is listed as an anti-cancer drug that can be treated regardless of cancer type
The NTRK gene plays an essential role in the physiology, development and function of the nervous system through the TRK protein, which causes problems when unrelated genes are combined. This phenomenon, called NTRK gene fusion, produces a fusion TRK protein that transmits abnormal signals. Eventually, the downstream pathway becomes hyperactive, causing problems in cell growth and survival, leading to cancer.
All cancers can be caused by NTRK gene fusion, but they vary in frequency from cancer to cancer. There are very few cases of NTRK gene fusion in commonly
(same@dailypharm.com)
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