Optimal doses of Effient and Brilinta different for Koreans
By Eo, Yun-Ho | translator Alice Kang
21.07.21 16:14:45
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After the introduction of the ¡®East Asian Paradox,¡¯ various domestic studies have supported the theory
Efficacy demonstrated with half-dose¡¦ a customized, large-scale clinical study is required to verify the results
The theory that East Asians, including Koreans, require dose adjustments when receiving dual antiplatelet therapy (DAPT) prescriptions is gaining strength.
In other words, the ¡®East Asian Paradox¡¯ theory that antithrombotics' clinical effect and safety are different for East Asians compared to Westerners is now being recognized worldwide.
In Korea, with Young-Hoon Jung, director of the Cardiovascular Center at Gyeongsang National University Hospital, marking the start, domestic researchers have emphasized that East Asians show a different response to antithrombotics due to their lower risk of atherothrombotic events and a higher risk for serious bleeding events than Westerners and that an
Eo, Yun-Ho(unkindfish@dailypharm.com)
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