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Optimal doses of Effient and Brilinta different for Koreans

By Eo, Yun-Ho | translator Alice Kang

21.07.21 16:14:45

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After the introduction of the ¡®East Asian Paradox,¡¯ various domestic studies have supported the theory

Efficacy demonstrated with half-dose¡¦ a customized, large-scale clinical study is required to verify the results

The theory that East Asians, including Koreans, require dose adjustments when receiving dual antiplatelet therapy (DAPT) prescriptions is gaining strength.

In other words, the ¡®East Asian Paradox¡¯ theory that antithrombotics' clinical effect and safety are different for East Asians compared to Westerners is now being recognized worldwide.

In Korea, with Young-Hoon Jung, director of the Cardiovascular Center at Gyeongsang National University Hospital, marking the start, domestic researchers have emphasized that East Asians show a different response to antithrombotics due to their lower risk of atherothrombotic events and a higher risk for serious bleeding events than Westerners and that an

Eo, Yun-Ho(unkindfish@dailypharm.com)
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