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Liver cancer pioneer ¡®Nexavar,' the star in its guidelines

By Eo, Yun-Ho | translator Alice Kang

21.09.30 14:45:29

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Blockbuster anticancer drug | Episode 5: Nexavar

Had maintained its sole lead for over a decade¡¦ only drug recommended as first-line

Situation has changed with the introduction of competitor drugs¡¦ sales have decreased since patent expiry





There are two reasons why new drug development is slow for a certain disease: its marketability is low or the development of the drug is difficult.

When developed, new drugs developed in the latter situation attract more widespread attention. Liver cancer (hepatocellular carcinoma) is a typical example of this. And the only targeted anticancer therapy that was available in this difficult-to-develop field of liver cancer for over 10 years was ¡®Nexavar (sorafenib).¡¯

Of course, new drugs are now available, such as ¡®Stivargar (regorafenib)¡¯ as second-line treatment, and ¡®Lenvima (Lenvatinib),¡¯ which is used as first-line treatment like Nexavar. Also, an immunotherap

Eo, Yun-Ho(unkindfish@dailypharm.com)
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