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Pfizer applies for reimbursement of 3rd-gen ALKi Lorviqua

By Eo, Yun-Ho | translator Alice Kang

21.10.19 15:26:04

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Designated as an orphan drug¡¦ is in its listing process after being approved in July

Is expected to address drug resistance issue of previously introduced drugs, including ¡®Xalkori¡¯


Pfizer is aiming to introduce a second ALK inhibitor after ¡®Xalkori¡¯ into Korea¡¯s prescription market.

According to industry sources, Pfizer Korea has recently submitted a reimbursement listing application for its anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor (TKI), ¡®Lorviqua (lorlatinib),¡¯ which is in progress.

Pfizer received the orphan drug designation for Lorviqua last March, then in July, the drug was approved as monotherapy to treat adult patients with ALK-positive advanced non-small-cell lung cancer (NSCLC) whose disease has progressed after - Alecensa (alectinib) or Zykadia (ceritinib) as the first ALK tyrosine kinase inhibitor (TKI) therapy; or Xalkori (crizot

Eo, Yun-Ho(unkindfish@dailypharm.com)
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