The number of drugs that completed drug price negotiations between the NHIS and pharmaceutical companies increased significantly from 15 years ago. As drug price negotiations began in earnest in 2007, the expansion of PVA negotiations is believed to be the cause.

According to the NHIS' recent list of drugs that completed drug negotiations, the number of drugs that completed drug negotiations exploded from only 10 in 2007 to 307 in 2020. Drug price negotiations began in May 2006 with the introduction of a "plan to optimize drug costs" to stabilize health insurance finances. At the end of that year, guidelines for drug price negotiations were enacted, PVA negotiations as well as new drug drug negotiations