The Ministry of Food and Drug Safety (MFDS) announced on the 20th that it has approved Tavalisse Tab 100 mg (fostamatinib sodium hydrate), an orphan drug used to treat immune thrombocytopenia in adults.

Adult immune thrombocytopenia is an autoimmune disease in which antibodies against platelets are produced and platelets are destroyed in the spleen, resulting in petechiae and purpuric spots on the skin.

Tavalisse inhibits the activation of spleen tyrosine kinase (Syk), which inhibits the production of antibodies against platelets, thereby preventing platelet destruction while also interfering with platelet ingestion by macrophage.

Spleen tyrosine kinase is a non-receptor t